Top Week 1 College Football Bets for Each Power 5 Conference Our college football staff has picked every key Week 1 game against the spread, and now the staff is examining which team is the strongest bet to cover in every Power 5 conference. Using the latest odds from William Hill before this piece publishes, here is who we think can win you some money. No. 11 Oregon (+3.5) vs. No. 16 Auburn The Tigers are starting a true freshman quarterback under the bright lights of AT&T Stadium in a game against a top-15 team that returns most of its 2018 defensive starters.