College Football Picks Against the Spread: Week 2 Here are the College Football picks against the spread for week two. After a rough week one, we look to bounce back with a great week of predictions. Each week, we will give you picks against the spread for several different College Football games. After week one, my current record against the spread is 3-4. We lost UNC, UCLA, Notre Dame, and Vanderbilt while we got Wisconsin, Alabama, and Florida State. Here are the College Football picks against the spread for week two.