College Football Week 1 Picks: Who Has the Edge on Opening Weekend? Week 1 is finally here. After the 2019 college football season officially kicked off with a pair of FBS games last weekend, things are ramped up in a big way starting Thursday night. While many top teams aren’t expected to be challenged in their openers, others, like Oregon and Auburn, have a lot already hinging on game one. Who will win that clash in Arlington, and will any favorites fall victim to an early upset? Our eight college football writers and editors make their straight-up picks for Week 1’s 12 most interesting games below, taking turns defending their answers.