College football Week 11 picks against the spread for every top-25 matchup No. 1 LSU meets No. 2 Alabama in the “Game of the Century,” and that is the main event on the Week 11 college football schedule. A matchup of 8-0 teams between No. 5 Penn State and No. 13 Minnesota at noon will serve as the appetizer before the 3:30 p.m. showdown between the Tigers and Crimson Tide. There are 16 games featuring top-25 teams, and Sporting News is hoping to stay hot on its weekly picks against the spread.