Fantasy Football Waiver Wire Pickups: Week 16 The line stops here for many fantasy football leagues. While some still play through the entire season, standard protocol now places the finals in Week 16. This is where I’m supposed to congratulate those still reading for making the championship. If you’re playing for a title this weekend, kudos. But hey, maybe you’re just trying to get your money back by winning the third-place game or hoping to sidestep an embarrassing last-place punishment.