College football Week 10 picks against the spread for every top-25 matchup
The college football season enters the midpoint this week, and Week 10 slate features two matchups between ranked teams.
No. 6 Florida and No. 8 Georgia meet in the “World’s Largest Outdoor Cocktail Party” at 3:30 p.m. on CBS with the SEC East and a potential College Football Playoff berth on the line on the line. The AAC will get the primetime spotlight, with No. 15 SMU traveling to No. 24 Memphis (7:30 p.m., ABC). Other than that, nine AP Top 25 teams are on a bye this week.
Here is a look at our record so far this season:
Straight up: 139-38, .785 (9-7 last week)
Against the spread: 97-80, .548 (10-6 last week)
Upset picks: 2-11, .154 (0-2 last week)
With that, Sporting News’ Week 10 picks against the spread for every top-25 team (odds provided courtesy of Sportsbook Review as of 10 a.m. ET on Tuesday, Oct. 29).
Thursday, Oct. 31
West Virginia at No. 12 Baylor (-17.5)
The Bears are 2-3 against the spread as favorites this season, and the Mountaineers have been blown out by an average of 24.3 points per game the last three weeks. Both teams had a bye week, and that leads to a tighter Big 12 contest.
Baylor wins 31-20 but FAILS TO COVER the spread.
Georgia Southern at No. 20 Appalachian State (-16.5)
Georgia Southern won this matchup 34-14 last season in a rain-soaked game, and they have warmed up with three straight victories. The Mountaineers are 3-2 against the spread as favorites this season, and this will be tight into the second half.
Appalachian State wins 34-21 but FAILS TO COVER the spread.
Saturday, Nov. 2
No. 14 Michigan (-19) at Maryland
The Wolverines are coming off a big win, but there is a hint of an emotional letdown here knowing they are 6-9-1 against the spread as road favorites under Jim Harbaugh. Mike Locksley and Josh Gattis feuded in the offseason, so this feels like the Terps’ all-in game. The back-door cover possibility will be there, but we like what the Wolverines found last week against the Irish.
Michigan wins 38-14 and COVERS the spread.
N.C. State at No. 23 Wake Forest (-7.5)
This is a big game for the Demon Deacons, knowing they still have an outside chance at the Playoff as long as they retain just one loss. The ACC has been as unpredictable as ever, but Wake Forest is 4-1 at home and poised to break that streak.
Wake Forest wins 31-24 but FAILS TO COVER the spread.
Virginia Tech at No. 16 Notre Dame (-17.5)
The Irish can’t let the Michigan loss bleed into a game against a Virginia Tech team they embarrassed 45-23 last season. The Hokies have won three straight games, and that line could tick down before kickoff. Virginia Tech can hang around because of their running game.
Notre Dame wins 33-24 but FAILS TO COVER the spread.
No. 6 Florida vs. No. 8 Georgia (-6)
This is Florida’s big opportunity after losing the last two meetings with the Bulldogs. The line has jumped up a few points from its open, and Georgia has given up 20 points or fewer in every game this season. It’s tough knowing Florida is 2-0 against the spread as an underdog, and those games were against Auburn and LSU. We just like Georgia a little more.
Georgia wins 27-20 and COVERS the spread.
No. 22 Kansas State (-5.5) at Kansas
Les Miles has led Kansas to three victories, which is a big story on its own. The Jayhawks are playing loose, but they are catching Kansas State at the wrong time. The Wildcats extend their winning streak to 11 in this rivalry. After five straight games as an underdog, K-State enjoys being a favorite.
Kansas State wins 34-24 and COVERS the spread.
Wofford vs. No. 4 Clemson (-47.5)
It’s a get-in, get-out game for the Tigers against Wofford, which is 5-2 on the season. Dabo Swinney can use anything for motivation at this point, right?
Clemson wins 55-10 but FAILS TO COVER the spread.
No. 9 Utah (-3) at Washington
Washington has won four in a row in this series and will have the advantage of playing at home. The Utes, however, have given up just 23 points in four games since losing to USC. Utah is more motivated here, too.
Utah wins 22-15 and COVERS the spread.
No. 17 Cincinnati (-23) at East Carolina
The Bearcats are alive in the New Year’s Day 6 bowl conversation. The Bearcats are 5-2 against the spread and had a bye week to get ready for this business trip on the road. That spread looks a touch high.
Cincinnati wins 38-17 but FAILS TO COVER the spread.
Ole Miss at No. 11 Auburn (-19)
The Tigers suffered their second loss of the season on Saturday. Aside from the 59-31 loss to Alabama, the Rebels haven’t lost a game by more than 11 points this season. Perhaps they hang around a little bit longer against the Tigers.
Auburn wins 33-16 but FAILS TO COVER the spread.
No. 15 SMU at No. 24 Memphis (-6)
SMU and Memphis get the primetime treatment in what should be a fast-paced thriller. The Tigers have been favored in every game and are 5-3 against the spread. Brady White outplays Shane Buechele in a shootout.
Memphis wins 45-38 and COVERS the spread.
No. 7 Oregon (-4.5) at USC
Oregon is in the Playoff mix, and games against USC always make the most impact. USC rallied from a 10-point deficit against Colorado and needs this one for bowl eligibility. The Ducks show off for the committee here.
Oregon wins 34-21 and COVERS the spread.
No. 21 Boise State (-17) at San Jose State
The Spartans are 0-13 against the Broncos, for those interested in the money line. If Boise State wants to impress the Playoff committee, then the Broncos have to pour it on here. They will.
Boise State wins 40-19 and COVERS the spread.